Multiple Choice Questions and Answers on ATP Synthesis and Fatty Acid Oxidation
Question 1 : The transport of acyl-CoA for oxidation using a shuttle involves formation of the intermediate
- 3 acetyl-CoA
- Acyl-coenzyme A
- acyl-carnitine
- None of these
Answer : 3
Question 2 : The maximum energy per gram on oxidization is yielded from
- fat
- protein
- glycogen
- starch
Answer : 1
Question 3 : The oxidation of methanol (wood alcohol) in human retina tissue indirectly leads to
- pressure builds up
- colour blindness
- blindness
- all of these
Answer : 3
Question 4 : Each cycle of β-oxidation produces
- 1 FADH2, 1 NAD+, and 1 acetyl-CoA
- 1 FADH2, 1 NADH and 1 acetyl-CoA
- 1 FADH2, 1 NADH and 2 CO2 molecules
- 1 FAD, 1 NAD+ and 2 CO2 molecules
Answer : 2
Question 5 : The three identical b subunits of the F1, complex during ATP synthesis have
- different affinities for ATP but not for ADP
- different affinities for ADP but not for ATP
- different affinities for ATP and for ADP
- similar affinities for ADP and ATP
Answer : 3
Question 6 : Where the acyl-CoA formed in the cytosol is transported for oxidation?
- Mitochondrial matrix
- Microsomes
- Endoplasmic reticulum
- Remains in cytosol
Answer : 1
Question 7 : Membrane potential and the proton gradient
- are both required to make ATP
- are sufficient, separately, to make ATP from ADP + Pi;
- reinforce one another when respiratory inhibitors are present
- cancel one another when uncouplers are present
Answer : 1
Question 8 : The irreversibility of the thiokinase reactions (formation of initial acyl-CoA)
- make this activation reaction the committed step on the pathway
- is due to the subsequent hydrolysis of the product
- applies only to even-chain fatty acids
- both (1) and (2)
Answer : 4
Question 9 : Long-chain fatty acids are oxidized step-wise in one carbon units starting from the
- carboxyl end
- aliphatic end
- both (1) and (2)
- none of these
Answer : 1
Question 10 : How many molecules of acetyl-CoA are produced in oxidation of palmitic acid (C16), which involves seven rounds of oxidation?
- 6
- 7
- 8
- 9
Answer : 3
Question 11 : The oxidation of methanol (wood alcohol) in human retina tissue leads directly to the formation of
- formaldehyde
- sugars
- CO2
- none of these
Answer : 1