Multiple Choice Questions and Answers on Gene Transfer in Plants
Question 1 : Which of the following are used as selection marker for the cells transformed with Agrobacterium?
- Neomycin phosphotransferase
- Streptomycin phosphotransferase
- Hygromycin phosphotransferase
- any of the above
Answer : 4
Question 2 : Vir genes required for the T-DNA transfer and processing are located
- on the T-DNA
- outside the T-DNA region
- on the plant genome
- none of these
Answer : 2
Question 3 : Plant transformation vectors based on Agrobacterium can generally be divided into
- two vectors
- four vectors
- six vectors
- eight vectors
Answer : 1
Question 4 : T-DNA transfer and processing into plant genome requires products of which of the following genes?
- vir A,B
- vir G,C
- vir D,E
- All of these
Answer : 4
Question 5 : Because of large size of Ti-plasmid, intermediate vectors (IV) are developed in which T DNA has been subcloned into
- pBR 322 based plasmid vector
- pRK 2013
- pRN 3
- all of these
Answer : 1
Question 6 : The transfer of intermediate vectors into Agrobacterium are brought about by
- transformation
- biparental mating
- triparental mating
- transduction
Answer : 3
Question 7 : In response to the activating signal molecule, an endonuclease is produced that causes nicks in the T-DNA. It is encoded by
- vir A
- vir B
- vir C
- vir D
Answer : 4
Question 8 : Microinjection involves
- injection of large amount of DNA
- injection of DNA into bigger cells
- injection with needle having diameter greater than cell diameter
- all of the above
Answer : 3
Question 9 : Which of the following is not true for microinjection technique that involves transfer of DNA into protoplast?
- It is carried out with the help of micromanipulator
- The recipient cells are immobilized on artificial support or artificially bound to substarate
- It employs needle with diameter greater than cell diameter
- all of the above
Answer : 3
Question 10 : The right segment of octopine T-DNA (TR) is necessary for
- enzymes for agropine biosynthesis
- tumour formation
- conjugative transfer
- all of these
Answer : 1
Question 11 : Opine synthesis is the property
- conferred to plant cells when it transformed by Agrobacterium tumefaciens
- determined by the bacteria Agrobacterium tumefaciens
- both (1) and (2)
- of normal plant cells
Answer : 3
Question 12 : Virulent strains of Agrobacterium contain large Ti-plasmids, which are responsible for the DNA transfer and subsequent disease symptoms. It has been shown that Ti-plasmids contain
- one set of sequence necessary for gene transfer
- two sets of sequence necessary for gene transfer
- three sets of sequence necessary for gene transfer
- four sets of sequence necessary for gene transfer
Answer : 2
Question 13 : The direct repeats flanking the T-DNA of Agrobacterium tume-faciens are known as
- cos site
- flanking sequences
- border sequences
- transfer sequences
Answer : 3
Question 14 : Opines that are present in crown gall tumour include
- octopine
- nopaline
- agropine
- all of these
Answer : 4
Question 15 : Intermediate vectors containing T-DNA are conjugation deficient. Thus conjugation is mediated in presence of which of the following plasmid?
- pRK 2013
- pRN 3
- either (1) or (2)
- none of these
Answer : 3
Question 16 : Which of the following is true about T DNA?
- Integration of T DNA can occur at many different, apparently random, sites in the plant nuclear DNA
- Integration of T DNA occurs only at one specific sites in the plant nuclear DNA
- Integration of T DNA occurs at two specific sites in the plant nuclear DNA
- Integration of T DNA occurs at one site that may be random in the plant nuclear DNA
Answer : 1
Question 17 : Which of the following is not true about the direct repeats flanking T-DNA?
- They are conserved between nopaline and octopine Ti-plasmids
- These repeats are transferred intact to the plant genome
- These are important in integration mechanism
- all of the above
Answer : 2
Question 18 : The left segment of octopine T-DNA (TL) is necessary for
- enzymes for agropine biosynthesis
- tumour formation
- conjugative transfer
- all of these
Answer : 2
Question 19 : Microprojectile method of gene transfer in plants involves delivery of DNA
- with the help of micromanipulator
- with the help of bolistics
- with the help of needles
- any of the above
Answer : 2
Question 20 : Which of the following genes are constitutively expressed and control the plant induced activation of other vir genes?
- vir A and vir G
- vir C and vir D
- vir B and vir E
- vir A and vir B
Answer : 1
Question 21 : Integrated octopine T DNA occurs as
- single segment
- two segments
- three segments
- four segments
Answer : 2
Question 22 : Liposomes mediated gene transfer in plants involves
- plasmid DNA enclosed in a lipid bag
- fusion of liposomes with protoplast
- use of polyethylene glycol (PEG)
- all of the above
Answer : 4
Question 23 : Which of the following plant signal molecules regulate the expression of vir B, C, D and E in case of tobacco?
- Acetosyringone
- α-hydroxy syringone
- Both (1) and (2)
- None of these
Answer : 3
Question 24 : Which of the following is true about Agrobacterium tumefaciens?
- It causes crown gall disease of plants
- It infects gymosperms
- It infects dicotyledonous angiosperms
- All of the above
Answer : 4
Question 25 : In the liposome mediated gene transfer in plants, nucleic acids are
- protected from nuclease digestion
- stable in liposomes
- both (1) and (2)
- not stable in liposomes
Answer : 3
Question 26 : Advantage of microprojectile method over microinjection method for gene transfer in plants include
- intact cells are used
- method is universal in its application irrespective of all shape, size, type and presence or absence of cell wall
- gene can be transferred to many cells simultaneously
- all of the above
Answer : 4
Question 27 : On Ti-plasmid T-region or T-DNA is flanked by a direct repeat of
- 12 bp
- 20 bp
- 25 bp
- 30 bp
Answer : 3
Question 28 : Agrobacterium tumefaciens is a
- gram (+) bacteria
- gram (-) bacteria
- a fungi
- a yeast
Answer : 2
Question 29 : In a plant tumour cell
- complete Ti plasmid is incorporated in plant nuclear DNA
- different parts of the Ti-plasmid are incorporated
- only a small specific segment of callus T DNA is incorporated
- may vary from plant to plant
Answer : 3
Question 30 : Co-integrating transformation vectors must include a region of homology in
- the vector plasmid
- the Ti-plasmid
- between vector plasmid and Ti-plasmid
- none of these
Answer : 3
Question 31 : Crown gall tissue
- can be cultivated in vitro in absence of bacteria
- retains tumorous properties when cultivated
- both (1) and (2)
- shows tumorous properties only in presence of bacteria
Answer : 3
Question 32 : Integrated nopaline T-DNA occurs as
- single segment
- two segments
- three segments
- four segments
Answer : 1
Question 33 : Opines are
- amino acid derivatives found in tumor tissues
- amino acid derivatives found in normal tissues
- amino acid derivatives found in normal tissuesamino acid derivatives found in both normal as well as tumor tissues
- none of the above
Answer : 1
Question 34 : Virulence trait of Agrobacterium tumefaciens is borne on
- chromosomal DNA
- tumour inducing plasmid DNA
- both chromosomal and plasmid DNA
- cryptic plasmid DNA
Answer : 2
Question 35 : The size of the virulent plasmid of Agrobacterium tumefaciens is
- 40-80 kb
- 80-120 kb
- 140-235 kb
- >235 kb
Answer : 3
Question 36 : Which of the following is not true about the helper plasmids?
- These can replicate in Agrobacterium
- These help in the mediating conjugation of intermediate vectors
- These can’t replicate in Agrobacterium
- All of the above
Answer : 1
Question 37 : Which technique is used to introduce genes into dicots?
- electroporation
- particle acceleration
- microinjection
- Ti plasmid infection
Answer : 4
Question 38 : Direct DNA uptake by protoplasts can be stimulated by
- polyethylene glycol (PEG)
- decanal
- luciferin
- all of these
Answer : 1