Multiple Choice Questions and Answers on Protein Structure
Question 1 : The four subunits of the hemoglobin (Hb) gene represent protein’s
- primary structure
- secondary structure
- tertiary structure
- quaternary structure
Answer : 4
Question 2 : Marfan’s syndrome is thought to be a mutation affecting
- hemoglobin synthesis
- collagen synthesis
- metabolism of homogentisic acid
- insufficient thyroid production
Answer : 2
Question 3 : Cyclins are proteins that
- regulate ability of cells to invade tissue
- regulate passage from one stage of cell division to another
- regulate apoptosis of damaged cells
- none of the above
Answer : 2
Question 4 : Over 50% of common cancers are associated with damage to a protein, p53. This protein
- is a cyclin
- is a tumor supressor
- is an oncogene
- regulates apoptosis
Answer : 2
Question 5 : Protein folding is
- automatic, mediated by the protein itself
- mediated by other proteins called chaperones
- mediated by the ribosomes
- none of the above
Answer : 2
Question 6 : Sickle cell disease is due to
- a mutation in the beta chain of Hb
- a mutation in the alpha chain of Hb
- infection with a parasite
- none of the above
Answer : 1
Question 7 : Beta pleated sheets are examples of protein’s
- primary structure
- secondary structure
- tertiary structure
- quaternary structure
Answer : 2
Question 8 : BRACl, an inherited form of breast cancer, regulates cell division by
- binding to a DNA sequence
- complexing with cyclins
- binding to the cell outer membrane
- binding to the protein RAD 51 which repairs DNA damage
Answer : 4
Question 9 : Metastasis involves
- ability of cells to dissolve cellular matrix
- metalloprotein levels
- decreased levels of proteins that regulate metalloproteins
- all of the above
Answer : 4
Question 10 : Signal sequences are part of a protein that
- signal folding of the protein
- signal the protein synthesis on the ribosomes is ended
- transport proteins to other sites within the cell
- refold proteins in prion-associated diseases
Answer : 3
Question 11 : Individuals with PKU disease are mentally retarded unless
- phenylalanine in the diet is restricted
- phenylalanine in the diet is restricted
- homogentisic acid in the diet is restricted
- none of the above
Answer : 1