Protein Structure Questions and Answers

Multiple Choice Questions and Answers on Protein Structure

Question 1 : The four subunits of the hemoglobin (Hb) gene represent protein’s

  1. primary structure
  2. secondary structure
  3. tertiary structure
  4. quaternary structure

Answer : 4

Question 2 : Marfan’s syndrome is thought to be a mutation affecting

  1. hemoglobin synthesis
  2. collagen synthesis
  3. metabolism of homogentisic acid
  4. insufficient thyroid production

Answer : 2

Question 3 : Cyclins are proteins that

  1. regulate ability of cells to invade tissue
  2. regulate passage from one stage of cell division to another
  3. regulate apoptosis of damaged cells
  4. none of the above

Answer : 2

Question 4 : Over 50% of common cancers are associated with damage to a protein, p53. This protein

  1. is a cyclin
  2. is a tumor supressor
  3. is an oncogene
  4. regulates apoptosis

Answer : 2

Question 5 : Protein folding is

  1. automatic, mediated by the protein itself
  2. mediated by other proteins called chaperones
  3. mediated by the ribosomes
  4. none of the above

Answer : 2

Question 6 : Sickle cell disease is due to

  1. a mutation in the beta chain of Hb
  2. a mutation in the alpha chain of Hb
  3. infection with a parasite
  4. none of the above

Answer : 1

Question 7 : Beta pleated sheets are examples of protein’s

  1. primary structure
  2. secondary structure
  3. tertiary structure
  4. quaternary structure

Answer : 2

Question 8 : BRACl, an inherited form of breast cancer, regulates cell division by

  1. binding to a DNA sequence
  2. complexing with cyclins
  3. binding to the cell outer membrane
  4. binding to the protein RAD 51 which repairs DNA damage

Answer : 4

Question 9 : Metastasis involves

  1. ability of cells to dissolve cellular matrix
  2. metalloprotein levels
  3. decreased levels of proteins that regulate metalloproteins
  4. all of the above

Answer : 4

Question 10 : Signal sequences are part of a protein that

  1. signal folding of the protein
  2. signal the protein synthesis on the ribosomes is ended
  3. transport proteins to other sites within the cell
  4. refold proteins in prion-associated diseases

Answer : 3

Question 11 : Individuals with PKU disease are mentally retarded unless

  1. phenylalanine in the diet is restricted
  2. phenylalanine in the diet is restricted
  3. homogentisic acid in the diet is restricted
  4. none of the above

Answer : 1