Thermodynamics and Free Energy Questions and Answers

Multiple Choice Questions and Answers on Thermodynamics and Free Energy

Question 1 : The unfolding of regular secondary structure causes

  1. little increase in the entropy of protein
  2. large decrease in the entropy of the protein
  3. no change in the entropy of the protein
  4. large increase in the entropy of the protein

Answer : 4

Question 2 : During the unfolding reaction of a helix, breakage of each hydrogen bond requires about 2kJ/mol. This implies hydrogen bonds are

  1. not reformed with water
  2. much stronger in proteins than in water
  3. slightly weaker in proteins than in water
  4. slightly stronger in proteins than in water

Answer : 4

Question 3 : If the enthalpy change for a reaction is zero, ΔG° is equal to

  1. TΔS°
  2. -TΔS°
  3. -ΔH°
  4. lnKeq

Answer : 2

Question 4 : Reactions that have positive standard free energy changes (ΔGo> 0) can be made to occur in cells by

  1. coupling them with exergonic reactions via a common intermediate
  2. manipulating the concentrations of products and reactants such that G/<0
  3. coupling them to the hydrolysis of ATP
  4. all of the above

Answer : 4

Question 5 : The Standard Gibb’s free energy, ΔG°, is

  1. the residual energy present in the reactants at equilibrium

the residual energy present in the products at equilibrium

the difference in the residual energy of reactants and products at equilibrium

the energy required to convert one mole of reactants to one mole of products

Answer : 4

Question 6 : If the Standard Gibb’s free energy, ΔG°, for a reaction is positive then

  1. the products will be favored
  2. the reactants will be favored
  3. the concentration of the reactants and products will be equal
  4. all of the reactant will be converted to product

Answer : 2